ABSTRACT: AIM: To assess the effectiveness of structured teaching programme on knowledge regarding psychoactive substance use and its harmful effects among college students at selected university Bhopal Madhya Pradesh. MATERIAL AND METHODS: A quasi- experimental research with one group pre-test post-test design was used and the study was conducted in college Institute of Polytechnic Engineering students at R.K.D.F. University Bhopal Madhya Pradesh. The population consist of college students. The sample size was 60 college students of Institute of Polytechnic Engineering, who fulfilled the inclusion criteria. The tool used for data collection was structured questionnaire. RESULTS: the study finding revealed that among 60 Institute of Polytechnic Engineering students 28(46.66%) had inadequate knowledge, 21(35%) had moderate knowledge and 11(18.33%) had adequate knowledge in pre-test, after administration of structured teaching programme, the post-test findings revealed that 5(8.33%) had inadequate knowledge, 16(26.66%) had moderate knowledge and 39(65%) had adequate knowledge. Conclusion: College students had gained knowledge on psychoactive substance use and its harmful effects after the structured teaching programme in the post test assessment. KEY WORDS: Structured teaching programme, psychoactive substance, harmful effects, Adolescent, College Students, Substance Use.

ABSTRACT: A   simple,   precise   and   accurate   method   for   simultaneous   estimation   of   Candesartan   Cilexetil (CAN)   and   Amlodipine   Besylate   (AML)   in   a   synthetic   mixture   using   methanol   as   solvent.   The   First method   is   Area   under   curve   method   (Method   A)   for   that   wavelength   ranges   selected   were   247.80 -   257.80   nm   for   CAN   and   230   -   240   nm   for   AML   and   area   were   integrated   between   these   selected wavelength   ranges   for   both   drugs.   The   second   method   is   First   order   derivative   method   in   which CAN   shows   zero   crossing   point   (ZCP)   at   240.40   nm   (For   estimation   of   AML)   and   AML   shows   ZCP   at 224.20   nm   (For   estimation   of   CAN).   Beer’s   law   is   obeyed   in   the   concentration   range   of   8   –   24 µg/ml   for   CAN   and   5   –   15   µg/ml   for   AML   respectively.   The   mean   %   Recoveries   was   found   to   be   in range   of   99.15   –   100.35%   for   CAN   and   98.07   –   101.59%   for   AML   by   Area   under   curve   method   and 99.21   –   100.66%   for   CAN   and   98.99   –   100.02%   for   AML   by   First   order   derivative   method.   Both methods were validated as per ICH Q2 (R1) guideline. KEYWORDS: Candesartan Cilexetil (CAN), Amlodipine Besylate (AML), Area Under Curve method (AUC), First order derivative method, Synthetic mixture.

ABSTRACT: The oral route is the most preferred route for the administration of various drug because it is the most convenient and safest route for drug delivery. Recently fast dissolving tablet (FDT) is developed by the researcher. This improved patient compliance and convenience. Fast dissolving tablet are defined as the solid dosage form which disintegrates in saliva without the need for water. Solid dispersions attract considerable interest by increasing dissolution rate and also enhance the bioavailability of poorly water-soluble drugs. Pre-gastric absorption avoids first-pass hepatic metabolism which increases the bioavailability of the drug. One part of the review article focus on solid dispersion, there advantages, disadvantages and method of preparation. Later part of the review article focus on the evaluation of fast dissolving tablet. KEYWORDS: Fast dissolving tablet, Oral route, Solid dispersion, Method of preparation.

ABSTRACT: Background   of   the   study:   Bachelor   level   nursing   students   have   less   knowledge   on   Nipah   Virus.   Nipah   virus   (NiV) infection   is   a   zoonotic   disease.   The   natural   host   of   Nipah   virus   is   fruit   bats   of   Pteropodidae   family.   Case   fatality   of NiV   infection   ranges   from   40-75%.   There   are   currently   no   vaccines   approved   for   human   use.   Thus,   it   is   necessary   to raise   their   knowledge   level   regarding   NiV   infection.   Aims:   The   main   objective   of   the   study   to   assess   the   knowledge regarding    Nipah    virus    infection    among    the    nursing    students    before    and    after    educational    intervention. Methodology:   Pre-experimental   one   group   pre-test   design   was   used   among   70   nursing   students   from   University College    of    nursing.    Self-administered    questionnaire    consisting    demographic    characteristics    and    knowledge regarding   NiV   infection   was   used   before   and   after   an   educational   intervention.   Result:      Collected   data   were analyzed   by   using   descriptive   and   inferential   statistics.   The   result   of   the   study   reveals   that,   in   pre-test   64.25%   of respondents   had   inadequate   knowledge   level   27.14%   respondents   have   moderate   level   of   knowledge   and   8.57% respondents   had   adequate   knowledge   on   Nipah   Virus   Infection.   In   Post-test   48.57%   respondents   had   adequate knowledge   41.43%   had   moderate   knowledge   and   10%   respondents   had   inadequate   knowledge   on   Nipah   Virus Infection.   Interpretation   and   Conclusion:   significant   difference   was   found   between   the   pre-test   and   post-   test knowledge    levels    among    bachelor    level    nursing    students.    This    study    stipulates    most    of    the    respondents    had inadequate   knowledge   before   educational   intervention   and   all   the   most   of   the   respondents   had   satisfactory knowledge   after   educational   intervention.   Thus,   the   study   cease   that   in   order   to   raise   the   knowledge   of   nursing students on emerging disease education intervention will be beneficial. KEY WORDS: Nipah Virus, Niv, Pteropodidae, Educational Intervention, Bachelor Level Nursing Students.