ISSN 2277 - 3681
Indexing & Listing
Impact Factor-2.633
(JIF-2015)
Journal of
Pharmaceutical Science and Bioscientific Research
Volume 10
Issue 4, 2021
A Review on Analysis of Biosimilars
Priyal K Shah;, Manan Patel, Keshava Jetha, Dhaval M. Patel*, Riddhi Trivedi, Himika Rathi
A Review on Medicinal Plants Used in Treatment of Jaundice
Bhumika M Patel*, Madhuri Hinge
Review on Various Bioanalytical Methods Used for Determination of Drugs Used in Covid-19 Pandemic
Mansi R. Patel*, Madhuri Hinge
A Brief Review on Fast Protein Liquid Chromatography- FPLC
Hiral Prajapati*, Chirag Desai, Sachin Narkhede
Review on Different Analytical Methods to Detect Presence of Heavy Metals in Various Cosmetic Products
Hinal C. Rathod*; Shuchi P. Desai
ABSTRACT:
Literature suggests that biosimilars are similar biological products, i.e., comparable but not identical to the reference
product, are not generic version of innovator product and do not ensure therapeutic equivalence. Biosimilars present
more challenges than conventional generics and marketing approval is also more complicated. Other than that the
analysis of the developed biosimilar is also a critical point, as it varies in each category. Analysis of biosimilars acts a
crucial point for marketing approval as the data received acts as a base for response of the developed biosimilars.
KEY WORDS: Biosimilars, Chromatography, Spectroscopy, Analysis
![[x]](Issue_1_htm_files/close.png "Close")
ABSTRACT:
Liver is the most important vital organ of our body and is the most responsible organ for metabolism and secretory activities. Jaundice is
the major cause for the morbidity and mortality across the world. Liver problems is the worldwide problem in humans. Jaundice is the
diseases, which directly affect the liver organ and production of bilirubin increases. This disease can occur in adults, child and even in
elders. The jaundice is the life-threatening disorder, which is divide into the two parts, one is pre-hepatic, and another is post-hepatic. In
jaundice bilirubin plasma level increases which results in diarrhoea, gastrointestinal bleeding, anaemia, edema, weight-loss, lethargy,
seizures, coma and even death. There are many medicinal plants used in treatment of jaundice with less side effects. There are wide
varieties of herbs and plants that have high efficacy to cure the jaundice. So, there is need to analyse this medicinal plant used for
treatment of Jaundice. In present study we have concise the different analytical methods UV, HPLC, HPTLC etc. for the analysis of
medicinal plants.
KEY WORDS: Jaundice, hepatoprotective activity, Analytical methods, medicinal plants.
ABSTRACT:
There is a new public health emergency intimidate the world with the emergence and spread of 2019 novel corona virus (2019-
nCoV), also known as the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). These viruses are set of enveloped
viruses with non-segmented, contain single-stranded and positive-sense RNA genomes. Apart from infecting assortment of
economically important vertebrates such as pigs and chickens, there are six corona viruses have been known to infect human hosts
and it is cause respiratory diseases in human. The NaMe has beeN OrigiNated frOM the Outer friNge Or ―cOrONa Of eMbedded
enclosed protein. Members of the family Coronaviridae, that causes broad spectrum diseases of animal and human. The COVID-19
pandemic hastened the use of reuse drugs to treat COVID-19 patients worldwide. Different classes of drugs used for the treatment of
COVID-19. There are no FDA approved drugs or medication for the corona virus patients. A goal of bioanalytical method is the
quantitative analysis of a concentration of drug/ its metabolites in biological fluids such as blood, plasma, serum, urine and saliva or
in tissue extracts. Various bioanalytical methods used for the estimation of COVID-19 drugs such HPLC, LC-MS, LC-MS/MS, UHPLC
etc. Bioanalytical methods are based on physico-chemical and biological property of drug molecule.
KEY WORDS: Corona virus, Drugs used in covid-19, Bioanalytical methods, HPLC, LC-MS, LC-MS/MS, UHPLC methods
