ISSN 2277 - 3681
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Impact Factor-2.633
(JIF-2015)
Journal of
Pharmaceutical Science and Bioscientific Research
Volume 10
Issue 6, 2021
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AReview Article on Herbal Medicinal Approach to Prevent Covid-19 Infection
Heli Desai*, Alisha Patel, Deepali Mohapatra
Biological Evidence of Piperine: A review
Khaled Rashed
Phytochemical and Biological Evidence of Balanites aegyptiaca
Khaled Rashed
Awareness amongst Pharmacy Undergraduates about prevention and treatment of novel coronavirus: A survey study
Khushi Parmar, Urja Bhavsar, Hardi Shah, Dhruvi Patel, Chirag Desai
Analytical Method Development and Validation of Artesunate and Amodiaquine Hydrochloride in Combined Tablet Dosage Form
by High Performance Liquid Chromatography
Adebola Morufu Adekoya
A Study to Assess the Level of Knowledge Regarding Mental Illness Among Student in Selected Nursing Institute
Jessy. P Inego, Jyoti sharma
A Study to assess The Effectiveness of Honey Dates in Improving Haemoglobin Level among Adolescent
Girls with Anaemia in a Selected College at kanyakumari District
Gnana Freeda, Jyoti Sharma
ABSTRACT:
A simple, economic, specific and accurate reverse phase high performance liquid chromatographic method was developed for the
simultaneous determination of Artesunate (ART) and Amodiaquine hydrochloride (AMO) in tablet dosage form. The column used was Agilent
technologies 150 mm x 3.9 mm, 5μ particle size, C18 packing in isocratic mode, with mobile phase containing phosphate buffer and methanol
(30: 70) (v/v), pH 3.0 and injection volume of 20µL, with a flow rate of 1.0ml/min. and the detection were carried out by Diode Array Detector
with Variable Wavelength (DAD) at dual wavelengths, 225nm and 339 nm respectively for Artesunate and Amodiaquine HCl. The retention
times of artesunate and amodiaquine hydrochloride were both 1.3 minutes but extracted at different wavelength. The linearity for Artesunate
and Amodiaquine hydrochloride were in the range of range 10-60 µg/mL and 5-30 µg/ml respectively with correlation coefficient of r2 =0.996
and 0.995 for artesunate and amodiaquine respectively. The recoveries of artesunate and amodiaquine hydrochloride were found to be
102.9% and 102.9%, respectively. The % RSD from repeatability, intra and inter day precisions was found to be <2.0%. The proposed method
was statistically evaluated and can be applied for routine quality control analysis of artesunate and amodiaquine hydrochloride in tablets. The
method was validated as per ICH Q(2A) guideline.
KEY WORDS: Artesunate and Amodiaquine hydrochloride, HPLC, Method development, Analytical Method Validation, Forced degradation
studies
![[x]](Issue_1_htm_files/close.png "Close")
ABSTRACT:
In this pandemic time of COVID-19, where allopathy medicines are doing miracles and giving relief, our ancient
treasure; Ayurveda, herbal medicines and Homeopathy are a bliss. Traditional herbs like Ashwagandha, Giloy/Guduchi,
Tulsi, Curcumin, Amla, and Lemon are showing affective results in boosting immunity and mental trauma. This article
states the importance of traditional medicines in COVID-19 pandemic with an effective preventive approach.
KEY WORDS: Herbal Medicinal plant, Ayurveda, COVID-19 outbreak, Indian/ ancient medicine
ABSTRACT:
Piperine is the main compound present in black pepper, and is the carrier of its specific pungent taste, which is responsible for
centuries of human dietary utilization and worldwide popularity as a food ingredient. Piperine has diverse biological activities, such as
anti-inflammatory, anticancer, antiviral, anti-larvicidal, pesticide, anti-Alzheimer’s, antidepressant, and most importantly piperine is
known as the bioavailability enhancer. The current review article aims to explore various biological activities of piperine.
KEY WORDS: Piperine, chemical compounds, plants, bioactivities
ABSTRACT:
Balanites aegyptiaca Del. is known as desert date. It belongs to the family Balanitaceae and is distributed throughout the drier
parts of India. It is spiny shrub or tree up to l0 m tall, widely distributed in dry land areas of Africa and South Asia. It is traditionally
used in treatment of various ailments i.e., jaundice, intestinal worm infection, wounds, malaria, syphilis, epilepsy, dysentery,
constipation, diarrhea, hemorrhoid, stomach aches, asthma, and fever. It contains protein, lipid, carbohydrate, alkaloid, saponin,
flavonoid, and organic acid.
KEY WORDS: Balanites aegyptiaca:, chemical compounds, plants, bioactivities
ABSTRACT
Mental illness is one of the leading health problems worldwide. It affects the person in physiological and psychological response,
Majority of the population struggles from mental disorder every year. The aim of the study is to assess the knowledge of mental
illness among I year B.Sc. (N) students in selected nursing colleges of Kanyakumari District. Materials and Methods: Descriptive
survey design was adopted for this study. The sample consisted of 30 students. The conceptual framework utilized for the study is
Roys Adaptation Model. The investigators gave a brief introduction and detailed explanation regarding the purpose of the study. The
tool consists of two sections. Section A consists of demographic variables and section B consisted of structured questionnaire with
25 questions with having 4 alternatives regarding Mental illness. Knowledge was assessed using the structured questionnaire
through interview schedule. Conclusion: The finding shows that 56.66% of subjects are with adequate knowledge, 43.33% of
subjects are with moderate knowledge and none of subjects are with adequate knowledge. Also, it was found that there is a
significant association between the knowledge and demographic variables such as age, gender, religion, family history of mental
illness, socio economic background and sources of previous knowledge and no association between marital status and type of
family.
KEY WORDS: knowledge, mental illness, nursing students
ABSTRACT
Anaemia is an important common disease in India. Adolescent girls are a mainly in the most common vulnerable group. This study was done to assess the
effectiveness of honey dates in improving haemoglobin level among adolescent girls with anaemia in Bejan Singh Institute of Ophthalmology, Kanyakumari
District. The aim of this study was to increase the haemoglobin level by honey dates intervention. The research design adopted to this study was a pre-
experimental design. The study was conducted in Bejan Singh Institute of Ophthalmology, Kanyakumari District and 30 samples was collected by using
simple random sampling method. The demographic variables were assessed by using questionnaire method and the haemoglobin level was assessed by
using Sahli’s method before and after intervention. The intervention of daily 5 seedless dates, 10ml honey was given to adolescent girls daily for 30 days in
the morning. The collected data were analysed by using both descriptive and inferential statistical methods. The study findings revealed that Honey Dates is
an effective intervention to increase the haemoglobin level among adolescent girls with anaemia.
KEY WORDS: Effectiveness, Honey Dates, Adolescent Girls, Anaemia, Institute
